Fever and Febrile Convulsions /

Management of fever in children with febrile convulsions

01 What Others Say

  • Kids health info for parents

Fever in children

02 Clinicians Tools and Resources

  • BMJ 2008; 337:a1302: research article supports the use of combined paracetamol and ibuprofen . Dose paracetamol 15 mg per kg every 4-6  hrs ( maximum of 4 doses in 24 hrs) and ibuprofen 10 mg per kg every 6-8 hours (maximum of 3 doses in 24 hrs)
  • Results On an intention to treat basis, paracetamol plus ibuprofen were superior to paracetamol for less time with fever in the first four hours (adjusted difference 55 minutes, 95% confidence interval 33 to 77; P<0.001) and may have been as good as ibuprofen (16 minutes, −7 to 39; P=0.2). For less time with fever over 24 hours, paracetamol plus ibuprofen were superior to paracetamol (4.4 hours, 2.4 to 6.3; P<0.001) and to ibuprofen (2.5 hours, 0.6 to 4.4; P=0.008). Combined therapy cleared fever 23 minutes (2 to 45; P=0.025) faster than paracetamol alone but no faster than ibuprofen alone (−3 minutes, 18 to −24; P=0.8). No benefit was found for discomfort or other symptoms, although power was low for these outcomes. Adverse effects did not differ between groups

Paracetamol plus ibuprofen for the treatment of fever in children: randomised controlled trial.

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Last updated: 22/09/2011